Macrogol-EL V Macrogol-only
Comparison of macrogol* with electrolytes (Macrogol-EL) vs macrogol without electrolytes (Macrogol-only).
A clinical study comparing a macrogol product without electrolytes with a macrogol product with electrolytes found that there was no difference in terms of efficacy and side effects.1
Importantly, there were no clinically significant differences in plasma electrolyte levels. However, 85% of patients in the group taking the macrogol product without electrolytes were willing to continue treatment after 4 weeks, compared to 63% in the group taking the macrogol product with electrolytes.
Both Products Equally Effective - Mean Weekly Stool Frequencies
Y Axis = Average number of stools per week, X Axis = Time
More Patients Willing To Continue Treatment After 4 Weeks With Macrogol-Only Laxative†
Y Axis = % of patients, X Axis = Time
No clinically significant difference in plasma electrolyte levels. "When desired, switching … can be done in elderly individuals without compromising efficacy.”
1. Seinala L et aL Comparison of Polyethylene Glycol with and without Electrolytes in the Treatment of Constipation in Elderly Institutionalised Patients. Durgs Aging 2009 : 26(8):703-713.
*This study was done with macrogol 4000 which is a similar product to macrogol 3350.†Trend only not statistically different.
Always read the label. Use only as directed. If symptoms persist, see your healthcare professional.